2023 01 v.34;No.109 1-10
中药黄酮类化合物抗动脉粥样硬化研究进展
基金项目(Foundation):
国家自然科学基金区域创新发展联合基金重点项目(No.U21A20223);国家自然科学基金青年项目(No.81803761);;
中国博士后科学基金面上项目(No.2019M652144)
邮箱(Email):
yxp@cjlu.edu.cn;yangyongyao168@sina.com;
DOI:
中文作者单位:
中国计量大学生命科学学院浙江省生物计量及检验检疫技术重点实验室;
摘要(Abstract):
目的:总结了关于黄酮类化合物的结构和来源以及在动脉粥样硬化进展中最重要的作用机制,以期为黄酮类化合物药物的研究提供一定的理论基础。方法:大量体内外实验已证明黄酮类化合物有显著的抗动脉粥样硬化作用。它主要通过抗氧化、抗炎、抗血小板、扩血管和降血压、调节血脂以及对肠道菌群的调节等作用机制,来降低动脉粥样硬化发生风险。结果:黄酮类化合物的未来发展对动脉粥样硬化的发展有着显著的影响。结论:有必要对黄酮类化合物进行进一步研究,以期开发出有明确疗效且作用机制更加清楚的天然黄酮类药物。
关键词(KeyWords):
黄酮类化合物;;天然产物;;动脉粥样硬化;;心血管疾病
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基本信息:
DOI:
中图分类号:R285
引用信息:
[1]俞晓平,李轶维,王月等.中药黄酮类化合物抗动脉粥样硬化研究进展[J].中国计量大学学报,2023,34(01):1-10.
基金信息:
国家自然科学基金区域创新发展联合基金重点项目(No.U21A20223);国家自然科学基金青年项目(No.81803761);; 中国博士后科学基金面上项目(No.2019M652144)
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